1983-1986: Queen Mary College, University of London, BSc (Biochemistry and Microbiology)
1986-1991: University of Essex, PhD (Light-induced damage to biological systems, including investigation of potential porphyrin photosensitisers for Photodynamic Tumour Therapy.)
1992-2016: Postdoctoral Scientific Officer (general photosynthesis, photosynthesis under environmental stress conditions and excess light, plant physiology, carotenoid pigment analysis, the antioxidant biochemistry of leaves, novel methods of imaging oxidative stress in leaves, medical antioxidant biochemistry of vitamin E (a-tocopherol) and selenium in relation to human disease states, especially of the nervous system. Analysis of vitamin D compounds in fungi.
Research expertise Plant Physiology & Biochemistry Specifically;
Photosynthetic gas exchange
Fryer, M.J. (1992) Antioxidant activity of thylakoid vitamin E (alpha-tocopherol) Plant Cell Environ. 15: 381-392.
Fryer, M.J. (1993) Evidence for the photoprotective effects of vitamin E. Photochem. Photobiol.58: 304-312.
Fryer, M.J., Oxborough, K., Martin, B,Ort, D.R. and Baker, N.R. (1995) Factors associated with depression of photosynthetic performance of maize crops during early season growth using chlorophyll fluorescence. Plant Physiol.108: 761-767.
Nie, G-Y., Robertson, E.J., Fryer, M.J., Leech, R.M. and Baker, N.R. (1995) Response of the photosynthetic apparatus in maize leaves grown at low temperature to transfer to normal growth temperature. Plant Cell Environ.18: 1-12.
Andrews, J.R., Fryer, M.J. and Baker, N.R. (1995) Characterisation of chilling effects on photosynthetic performance of maize crops during early season growth using chlorophyll fluorescence. J. Exp. Bot.46: 1195-1203.
Fryer, M.J. (1996) Lipoxygenase and oxidative damage in cold-stressed maize. Redox Report2: 351-352.
Fryer, M.J., Andrews, J.R., Oxborough, K., Blowers, D.A. and Baker, N.R. (1998) Relationship between CO2 assimilation, photosynthetic electron transport and active oxygen metabolism in leaves of maize in the field during periods of low temperature. Plant Physiology116: 571-580.
Fryer, M.J. (1998) Vitamin E may slow kidney failure owing to oxidative stress. Redox Report3: 259-261.
Fryer, M.J. (1998) Vitamin E status and neurodegenerative disease. Nutritional Neuroscience1: 327-351.
Fryer, M.J. (1998) Vitamin E as a protective antioxidant in progressive renal failure. Nephrology 5:, 1-7.
Fryer, M.J. (1999) Treatment of acute renal failure with antioxidant vitamin E. Renal Failure21: 231-232.
Fryer, M.J. (1999) Still searching for the fountain of youth; recent advances in the genetics and biochemistry of ageing. The Biochemist 21: 13-18.
Creissen, G., Firmin, J., Fryer, M., Kular, B., Leylend, N., Reynolds, H., Pastori, G., Wellburn, F., Baker, N., Wellburn, A., and Mullineaux, P. (1999) Elevated glutathione biosynthetic capacity in the chloroplasts of transgenic tobacco paradoxically causes increased oxidative stress. Plant Cell, 11: 1277-1291.
Fryer, M.J. (1999) Antioxidants and Friedreich’s ataxia. Lancet354: 1300-1301
Fryer, M.J. (2000) Still life in oxidation hypothesis of atherogenesis. Lancet356: 166-167.
Fryer, M.J. (2000) Selenium and human health. Lancet356: 943-944.
Fryer, M.J. (2001) Vitamin E supplementation. Lancet357: 633-634.
Fryer, M.J., Oxborough, K., Mullineaux, P.M. and Baker, N.R. (2002) Imaging of photo-oxidative stress responses in leaves. J. Exp. Bot.53: 1249-1254.
Fryer, M.J., Ball, L., Oxborough, K., Karpinski, S., Mullineux, P.M. and Baker, N.R. (2003) Control of Ascorbate peroxidase 2 expression by hydrogen peroxide and leaf water status during excess light stress reveals a functional organisation of Arabidopsis leaves. Plant J. 33: 691-705.
Fryer, M.J., (2002) Rationale for clinical trials of selenium as an antioxidant for the treatment of the cardiomyopathy of Friedreich’s ataxia. Medical Hypotheses.58: 127-132.
Fryer, M.J., Ball, L., Oxborough, K., Karpinski, S., Mullineaux, P.M., Baker, N.R. (2003) Control of ascorbate peroxidase 2 expression by hydrogen peroxide and leaf water status during excess light stress reveals a functional organisation of Arabidopsis leaves. Plant J.33: 691-705.
Flors, C., Fryer, M.J., Waring, J., Reeder, B., Bechtold, U., Mullineaux, P.M., Nonell, S., Wilson, M.T., Baker, N.R. (2006) Imaging the production of singlet oxygen in vivo using a new fluorescent sensor, Singlet Oxygen Sensor Green. J. Exp. Bot.57: 1725-1734.
Fryer, M.J. (2006) Vitamin E and Nerves of Steel. pp 138-140. ‘Guide to a Healthy Planet’ University of Essex.
Fryer, M.J. (2006) Why do we need Selenium in our diets? pp 141-144. ‘Guide to a Healthy Planet’ University of Essex.
Fryer, M.J. (2009) Potential of vitamin E as an antioxidant adjunct in Wilson’s disease. Medical Hypotheses73: 1029–1030.